Publishing Organization

The journal publishing organization, Chinese Medical Multimedia Press, was established in 1987 and is supervised by the National Health Commission of the People's Republic of China and sponsored by the Chinese Medical Association. It has become an all-media professional publishing unit integrating electronic audiovisual, electronic journals, books, and Internet publishing qualifications and has published 43 electronic journals, forming the largest medical electronic journal cluster in China with great professional influence in the medical field.

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Host Organization

The journal host organization, the Chinese Medical Association (CMA), is a non-profit national academic organization in China. Established in 1915, the CMA now has 89 specialty societies and about 700,000 members in China. CMA edits and publishes 191 medical and popular science journals including print and electronic, books and over 3,000 products including audio-visual and digital. It is an important social force in the development of medical science and technology and a linkage between the government and medical professionals.

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Organizing Organization

The journal organizing organization, Shanghai University, was founded in 1922. It is ranked as the 22nd best university in China and is placed in the top 300 universities around the world. It is also supported by the national Double First-Class Initiative and holds profound academic traditions and outstanding research facilities, with 11 disciplines entering the top 1% of the ESI global rankings while material science, chemistry and engineering have already reached the top 1‰.

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Journal Data

166

Articles

84788

Article Views

1690

Article Downloads

43 days

Submission to Final Descision

25 days

Acceptance to Publication

Indexing & Archiving

The Biomaterials Translational is indexed and archived in the following databases

Articles

Four-dimensional-printed personalized shape memory NiTi implant for minimally invasive delivery in cavitary bone defect reconstruction

Zhuangzhuang Li Minxun Lu Shanfang Zou Ruicheng Liu Haoyuan Lei Yitian Wang Yuqi Zhang Yong Zhou Changchun Zhou Yi Luo* Li Min* Chongqi Tu*

, 0(0): 00009. https://doi.org/10.12336/bmt.25.00009

Integrating 4D printing technology in medical implants offers promising advancements for minimally invasive delivery (MID) and personalized orthopedic solutions. This study presents a 4D-printed shape memory nickel-titanium (NiTi) mesh implant for cavitary bone defect reconstruction, enabling a time-dependent shape transformation. Fabricated through selective laser melting (80 W laser power, 600 mm/s scanning speed, 70 μm hatch spacing, 25 μm layer thickness), the implant can be compressed during implantation and recover its original shape. Micro-computed tomography analysis confirmed high geometric fidelity (D50 = 58 μm), while scanning electron microscopy-energy dispersive spectroscopy analysis revealed a uniform microstructure and confirmed the homogeneous distribution of Ni/Ti across the mesh implant. Phase transformation testing showed that the austenite finish temperatures (austenite finish) of the as-built sample and the acid-washed sample were below the 37°C physiological threshold. Compression testing indicated that a force of 156 N was required for 30% deformation, with complete recovery to its pre-defined shape. Clinically, the implant reduced cortical bone fenestration by 20%. Post-operative imaging at 6 and 12 months showed excellent osseointegration and minimal residual cavities. Functional assessments at 12 months indicated excellent recovery, with a Musculoskeletal Tumor Society score of 29. In the present study, the clinical use of the 4D-printed mesh implant demonstrated not only satisfactory osteointegration but also a practical advantage in surgical handling. The shape recovery of the implant from a compressed state to its pre-designed shape allowed for MID and precise fit to the defect contour.

Supplementary Material | References | Related Articles

Advancements in physical therapy for osteoporosis treatment

Lingli Zhang Yuan Zhang Ruixi Chi Rui Ji Bo Hu* Bo Gao*

, 0(0): 00007. https://doi.org/10.12336/bmt.25.00007

Osteoporosis (OP) is a ubiquitous metabolic bone disease characterized by reduced bone mass and the deterioration of bone microarchitecture. One of its most serious complications, fractures, can induce substantial functional disabilities in patients and are associated with chronic health issues, thereby imposing both medical and economic burdens. At present, the predominant therapeutic approaches for OP include pharmacotherapy and physical therapy (PT). While pharmacotherapy has proven effective, it is not without its drawbacks, such as prolonged treatment durations and adverse effects due to medication. PT, also referred to as physiotherapy, stands out as the most cost-effective alternative treatment for OP. PT involves the application of natural or artificial physical agents, such as sound, light, cold, heat, electricity, and mechanical forces (including motion and pressure), to non-invasively and non-pharmacologically treat local or systemic dysfunctions or pathologies. Its objective is to restore the body’s inherent physiological functions. PT offers a diverse array of treatment options for patients with OP who are unsuitable for surgery or for whom surgical intervention is not viable. This review investigates the feasibility of identifying appropriate PT methods tailored to the needs of individuals with OP, with the intent of providing a scientific foundation for improved clinical practice.

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Advances in selenium research for bone and joint-related diseases: from pathophysiological mechanisms to therapeutic implications of selenium-based biomaterials

Hongyan Zhou Xuan Yao Shuhang Liu Yuheng Li Li Hu Jing Zhang Wenhui Hu* Shiwu Dong*

, 0(0): 00002. https://doi.org/10.12336/bmt.25.00002

Selenium is an essential trace mineral crucial for human health. The selenium-selenoprotein axis exerts biological effects that are associated with bone and joint health. The metabolism of selenium in vivo involves multiple physiological mechanisms and organs working synergistically to maintain selenium homeostasis. Studies underscore the roles of selenium in diverse physiological processes, including antioxidant defense, anti-inflammatory responses, immune regulation, osteogenesis, and thyroid hormone metabolism. Conditions such as Kashin–Beck disease, rheumatoid arthritis (RA), osteoarthritis (OA), and osteoporosis have been linked to selenium deficiency. Adequate selenium supplementation has been shown to prevent and treat bone and joint-related diseases. While numerous natural and synthetic selenium compounds have been explored for their therapeutic potential in bone and joint-related diseases, their narrow therapeutic windows pose challenges. In recent years, selenium-based biomaterials have been extensively studied and applied in biomedical research. These biomaterials exhibit reduced toxicity and enhanced bioavailability compared to inorganic and organic selenium, making them promising strategies for targeted selenium delivery. Selenium-based biomaterials provide a more efficient alternative for the treatment of bone defects, osteoporosis, osteosarcoma, OA, RA, and other related diseases. This review highlights the pathophysiological functions of selenium in maintaining bone and joint homeostasis and summarizes the current progress in utilizing selenium-based biomaterials for treating bone and joint-related diseases.

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Special Issues

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Catalytic Biomaterials for Disease Theranostics

Guest Editors: Yu Chen, Liang Chen
Submission Deadline: 28 February 2025

Hydrogel Microspheres and Regenerative Medicine in Biomaterials Translational

Guest Editors: Wenguo Cui, Yiting Lei
Submission Deadline: 25 January 2024

Composite Solutions for Biomedical Advancements

Guest Editors: Bin Li, Wei Xia, Song Chen
Submission Deadline: 31 July 2025

Advances in Sustainable Biomaterials Composites

Guest Editors: R.A. Ilyas, Norhayani Othman, Khoo Pui San
Submission Deadline: 31 December 2025
Announcement
08 June 2025
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